Optimization of one-step pelletization technology of Biqiu granules by Plackett-Burman design and Box-Behnken response surface methodology / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 4406-4410, 2015.
Article
de Zh
| WPRIM
| ID: wpr-279225
Bibliothèque responsable:
WPRO
ABSTRACT
First with the qualified rate of granules as the evaluation index, significant influencing factors were firstly screened by Plackett-Burman design. Then, with the qualified rate and moisture content as the evaluation indexes, significant factors that affect one-step pelletization technology were further optimized by Box-Behnken design; experimental data were imitated by multiple regression and second-order polynomial equation; and response surface method was used for predictive analysis of optimal technology. The best conditions were as follows: inlet air temperature of 85 degrees C, sample introduction speed of 33 r x min(-1), density of concrete 1. 10. One-step pelletization technology of Biqiu granules by Plackett-Burman design and Box-Behnken response surface methodology was stable and feasible with good predictability, which provided reliable basis for the industrialized production of Biqiu granules.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Température
/
Médicaments issus de plantes chinoises
/
Chimie
/
Chimie pharmaceutique
/
Méthodes
Type d'étude:
Prognostic_studies
langue:
Zh
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2015
Type:
Article