Effect of angiotensin II on potassium channels of ischemic ventricular myocytes of the guinea pig / 生理学报
Acta Physiologica Sinica
;
(6): 149-153, 2002.
Article
Dans Chinois
| WPRIM
| ID: wpr-279321
ABSTRACT
The experiments were carried out on guinea pig isolated ventricular myocytes by using whole-cell patch clamp. The effects of angiotensin II (Ang II) on potassium ion channels of acute ischemic myocytes were observed. Whole-cell patch clamp recordings showed that physiological potassium current, including delayed rectifier potassium current and inward rectifier potassium current were inhibited under the condition of simulated ischemia, and then further inhibited by treatment with Ang II. ATP-sensitive potassium currents were increased under simulated ischemia and were further enhanced by Ang II treatment.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Pharmacologie
/
Physiologie
/
Angiotensine-II
/
Canaux potassiques
/
Cellules cultivées
/
Ischémie myocardique
/
Biologie cellulaire
/
Myocytes cardiaques
/
Cochons d'Inde
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
Acta Physiologica Sinica
Année:
2002
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS