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Different Impact of Diabetes Mellitus on In-Hospital and 1-Year Mortality in Patients with Acute Myocardial Infarction Who Underwent Successful Percutaneous Coronary Intervention: Results from the Korean Acute Myocardial Infarction Registry
Article de En | WPRIM | ID: wpr-28113
Bibliothèque responsable: WPRO
ABSTRACT
BACKGROUND/AIMS: The aim of this study was to evaluate the impact of diabetes mellitus (DM) on in-hospital and 1-year mortality in patients who suffered acute myocardial infarction (AMI) and underwent successful percutaneous coronary intervention (PCI). METHODS: Among 5,074 consecutive patients from the Korea AMI Registry with successful revascularization between November 2005 and June 2007, 1,412 patients had a history of DM. RESULTS: The DM group had a higher mean age prevalence of history of hypertension, dyslipidemia, ischemic heart disease, high Killip class, and diagnoses as non-ST elevation MI than the non-DM group. Left ventricular ejection fraction (LVEF) and creatinine clearance were lower in the DM group, which also had a significantly higher incidence of in-hospital and 1-year mortality of hospital survivors (4.6% vs. 2.8%, p = 0.002; 5.0% vs. 2.5%, p < 0.001). A multivariate analysis revealed that independent predictors of in-hospital mortality were Killip class IV or III at admission, use of angiotensin converting enzyme inhibitors or angiotensin-II receptor blockers, LVEF, creatinine clearance, and a diagnosis of ST-elevated MI but not DM. However, a multivariate Cox regression analysis showed that DM was an independent predictor of 1-year mortality (hazard ratio, 1.504; 95% confidence interval, 1.032 to 2.191). CONCLUSIONS: DM has a higher association with 1-year mortality than in-hospital mortality in patients with AMI who underwent successful PCI. Therefore, even when patients with AMI and DM undergo successful PCI, they may require further intensive treatment and continuous attention.
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Texte intégral: 1 Indice: WPRIM Sujet Principal: Facteurs temps / Angioplastie coronaire par ballonnet / Loi du khi-deux / Modèles logistiques / Modèles des risques proportionnels / Enregistrements / Analyse multifactorielle / Études prospectives / Facteurs de risque / Résultat thérapeutique Type d'étude: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limites du sujet: Aged / Female / Humans / Male Pays comme sujet: Asia langue: En Texte intégral: The Korean Journal of Internal Medicine Année: 2012 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Facteurs temps / Angioplastie coronaire par ballonnet / Loi du khi-deux / Modèles logistiques / Modèles des risques proportionnels / Enregistrements / Analyse multifactorielle / Études prospectives / Facteurs de risque / Résultat thérapeutique Type d'étude: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limites du sujet: Aged / Female / Humans / Male Pays comme sujet: Asia langue: En Texte intégral: The Korean Journal of Internal Medicine Année: 2012 Type: Article