Correlation between periodontal disease and coronary atherosclerotic heart disease / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 169-172, 2006.
Article
Dans Chinois
| WPRIM
| ID: wpr-281239
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the correlation between coronary atherosclerotic heart disease (CAD) and periodontal disease (PD).</p><p><b>METHOD</b>Forty-five patients with CAD (CAD group) and 40 patients without CAD (control group) were compared with their pathological changes of periodontal tissues and inflammatory markers [high sensitive C reactive protein (hsCRP), interleukin-1beta (IL-1beta), and tumor necrosis factor-alpha (TNF-alpha)].</p><p><b>RESULTS</b>Univariate analysis showed that the prevalence of PD was 84.44% in CAD group and 22.50% in control group (P < 0.01). The levels of hsCRP, IL-1beta, and TNF-alpha were (5.75 +/- 1.26) mg/L, (10.32 +/- 2.96) ng/L, and (9.17 +/- 2.14) ng/L in CAD group and (1.13 +/- 0.73) mg/ L, (2.87 +/- 1.45) ng/L, and (5.84 +/- 1.96) ng/L in control group (P < 0.01). Gingival index and plaque index were statistically different between two both groups (P < 0.01). Logistic regression analysis showed that in addition to pulse pressure and low density lipoprotein cholesterol, periodontal disease index was a higher risk factor of CAD. Its relative risk was 1.217 (95% CI was 1.120-1.805, P < 0.05).</p><p><b>CONCLUSION</b>PD can cause CAD. The improvement of public oral health plays an important role in the prevention and treatment of CAD.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Maladies parodontales
/
Sang
/
Maladie des artères coronaires
/
Protéine C-réactive
/
Études cas-témoins
/
Indice parodontal
/
Indice de plaque dentaire
/
Facteurs de risque
/
Interleukine-1
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Facteurs de risque
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Acta Academiae Medicinae Sinicae
Année:
2006
Type:
Article
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