Analysis of anthraquinones in serum and urine after oral administration of semen Cassiae / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To analysie the anthraquinones absorbed into serum by different animals (or human beings) after oral administration of Semen Cassiae.</p><p><b>METHOD</b>Anthraquinones in serum and urine of rats and urine of healthy men after taking Semen Cassiae orally were detected with HPLC.</p><p><b>RESULT</b>Only some of the anthraquinones were absorbed into serum. There were differences in absorption and metabolism of anthraquinones between rats and men and some new anthraquinones were produced in the process.</p><p><b>CONCLUSION</b>Anthraquinones absorbed into serum by the experimental animals or men should become target for researching into active compounds of anthraquinones in Semen Cassiae.</p>