Effect of tiaozhi yanggan decoction in treating patients with non-alcoholic fatty liver / 中国结合医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To observe the clinical efficacy and safety of Tiaozhi Yanggan Decoction (TZYGD) in treating non-alcoholic fatty liver.</p><p><b>METHODS</b>One hundred and thirty-eight patients were enrolled and randomized into two groups according to the random number table in a ratio of 31, with 8 cases eventually dropping out. The symptoms, signs, liver function markers, blood lipids, iconographic indices and clinical comprehensive efficacy after a 12-week treatment course were assessed in 101 patients treated with TZYGD in the treated group and 29 patients treated with Thiola in the control group.</p><p><b>RESULTS</b>The total effective rate in the treated group and the control group was 81.19% and 68.97%, respectively, showing a significant difference between the two groups with the former being significantly higher than the latter (P<0.05). Moreover, the improvements in the symptoms, signs, liver function, blood lipids and iconographic indices in the treated group were favorable with no serious adverse reactions.</p><p><b>CONCLUSION</b>TZYGD is effective and highly safe in treating non-alcoholic fatty liver.</p>