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Analysis of pathogen isolated from lower respiratory tract in coalminer's pneumoconiosis patients complicated with infection / 中华劳动卫生职业病杂志
Chinese Journal of Industrial Hygiene and Occupational Diseases ; (12): 541-542, 2011.
Article Dans Chinois | WPRIM | ID: wpr-282552
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the composition and resistance of main pathogens isolated form Lower respiratory tract in coalminer's pneumoconiosis patients complicated with infection to provide the basis for clinical treatment.</p><p><b>METHOD</b>Coalminer's pneumoconiosis patients complicated with infection during 2009 to 2010 were divided into mechanical ventilation group and non mechanical ventilation group. Specimens were obtained from lower respiratory tract by fibrobronchoscopy with protected specimen brush in patients of both groups to perform isolation, culture, identification and susceptibility test of pathogen.</p><p><b>RESULT</b>Total 111 patients were enrolled, 36 of them in mechanical ventilation group and 75 patients in non mechanical ventilation group. The pathogenic bacteria detection rate of patients in mechanical ventilation group was significantly higher than that of patients in non mechanical ventilation group (88.9% vs. 46.7%, P < 0.01). In non mechanical ventilation group, Mycobacterium tuberculosis was detected in 3 patients, and 27 strains of G- bacilli, 3 strains of G+ coccus, and 2 strains of fungus; and 26 strains of G- bacilli, 3 strains of G+ coccus, and 3 strains of fungus were detected in mechanical ventilation group. There was no significant difference in term of strains between the two groups (P > 0.05). Rate of resistance to main antibiotics of patients in mechanical ventilation group was higher than that of patients in non mechanical ventilation group.</p><p><b>CONCLUSION</b>Resistance of pathogenic bacteria isolated from lower respiratory tract was severe in coalminer's pneumoconiosis patients complicated with infection, which was higher in patients treated with mechanical ventilation than patients without mechanical ventilation. Mycobacterium tuberculosis and fungal infection and increasing resistance prompted that clinicians must attach importance to rational drug use and keep to monitoring bacterial resistance.</p>
Sujets)
Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Ventilation artificielle / Infections de l&apos;appareil respiratoire / Résistance bactérienne aux médicaments / Anthracose / Microbiologie / Mycobacterium tuberculosis Limites du sujet: Adulte très âgé / Aged80 / Humains / Mâle langue: Chinois Texte intégral: Chinese Journal of Industrial Hygiene and Occupational Diseases Année: 2011 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Ventilation artificielle / Infections de l&apos;appareil respiratoire / Résistance bactérienne aux médicaments / Anthracose / Microbiologie / Mycobacterium tuberculosis Limites du sujet: Adulte très âgé / Aged80 / Humains / Mâle langue: Chinois Texte intégral: Chinese Journal of Industrial Hygiene and Occupational Diseases Année: 2011 Type: Article