Expression of nNOS, Pax3 and Cx43 proteins in early developing posterior horn of embryonic and fetal human spinal cord / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1651-1653, 2009.
Article
Dans Chinois
| WPRIM
| ID: wpr-282623
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the distribution pattern of the expressions neuronal nitric oxide synthase (nNOS), Pax3 and connexin 43 (Cx43) proteins in the early developing posterior horn of embryonic and fetal human spinal cord.</p><p><b>METHODS</b>Immunohistochemistry was used to detect the expressions of nNOS, Pax3 and Cx43 proteins in the posterior horn of the spinal cord during the second, third and fourth month of human embryonic and fetal development.</p><p><b>RESULTS</b>In the second to fourth month of gestation, the expressions of nNOS and Pax3 proteins increased gradually from weak expression to strong expression in the posterior horn of the spinal cord. In the second to third month of development, Cx43 protein expression was negative in the posterior horn of the spinal cord, but positive in the myelin sheath. In the fourth month, positive Cx43 expression was detected in some of the cells in the posterior horn of the spinal cord.</p><p><b>CONCLUSION</b>nNOS, Pax3 and Cx43 proteins are closely related to the growth and development of the spinal cord in human embryos and fetuses.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Connexine 43
/
Régulation de l'expression des gènes au cours du développement
/
Cellules de la corne dorsale
/
Biologie cellulaire
/
Embryon de mammifère
/
Nitric oxide synthase type I
/
Facteurs de transcription PAX
/
Foetus
/
Facteur de transcription PAX3
/
Métabolisme
Limites du sujet:
Femelle
/
Humains
/
Grossesse
langue:
Chinois
Texte intégral:
Journal of Southern Medical University
Année:
2009
Type:
Article
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