Application endoscopic mucosal resection to therapy early gastrointestinal cancer and precancerous lesion / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 488-491, 2006.
Article
Dans Chinois
| WPRIM
| ID: wpr-283291
ABSTRACT
<p><b>OBJECTIVE</b>To explore the clinical value of endoscopic mucosal resection (EMR) on early gastrointestinal cancer and precancerous lesion.</p><p><b>METHODS</b>The EMR data of 42 lesions from 28 patients, collected from Apr. 2001 to Dec. 2005, were retrospectively analyzed. All the lesions were confirmed histologically before and after operation.</p><p><b>RESULTS</b>Forty-two lesions were removed by the EMR from 28 patients. Lesion types observed under endoscopy were as follows type I 9 lesions (type Isp 2 lesions, type Is 7 lesions), type II 33 lesions (type IIa 23 lesions, type IIa + IIc 4 lesions, type IIb 6 lesions). Thirty-eight EMRs were performed by using snare resection techniques and 4 EMRs by using suction cap-assisted techniques. The size of lesions changed from 0.6 cm x 0.6 cm to 3.0 cm x 3.5 cm. Complete resections were achieved in 36 of 40, among them, 2 lesions were divided into 2 pieces and 1 lesion was divided into 3 pieces. Post-EMR histopathologic evaluation revealed the following</p><p><b>RESULTS</b>carcinoma in 4 lesions, high-grade dysplasia (HGD) in 11 lesions, middle-grade dysplasia (MGD) in 17 lesions, adenoma in 6 lesions, non-adenoma in 2 lesions. The pathology match rate between local biopsy and EMR was 60.0%. The detection rates of cancer, HGD and MGD by EMR were higher than that by routine biopsy. No serious complications were seen in this study.</p><p><b>CONCLUSION</b>Endoscopic mucosal resection has significant impact on the endoscopic intervention treatment of early cancer and precancerous lesion in digestive tract.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
États précancéreux
/
Tumeurs de l'estomac
/
Chirurgie générale
/
Tumeurs de l'oesophage
/
Études rétrospectives
/
Oesophagoscopie
/
Endoscopie
/
Gastrectomie
/
Muqueuse gastrique
Type d'étude:
Étude observationnelle
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Chinese Journal of Gastrointestinal Surgery
Année:
2006
Type:
Article
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