Stability of physical state on compound hawthorn dropping pills / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the stability of physical state with accelerate test and dropping in process before and after on compound hawthorn dropping pills.</p><p><b>METHOD</b>Scanning electron microscope, TG-DTA, FT-IR and XRD were used.</p><p><b>RESULT</b>The active components presented amorphous, tiny crystal and molecular state in dropping pills, and it had no obvious reaction between PEG 4000 and active components. With time prolonging, a little of active components changed from amorphous state to tiny crystal or molecular state.</p><p><b>CONCLUSION</b>Solid dispersion improved the stability and dissolution of compound hawthorn dropping pills.</p>