Expression of GIRK4 gene in kidney tissues of obese rat / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 36-39, 2013.
Article
de Zh
| WPRIM
| ID: wpr-284308
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the expression of GIRK4 gene in the kidney tissues of obese rats.</p><p><b>METHODS</b>Obese rat models were established using diet-induced method. The GIRK4 protein expression in kidney tissues was determined in 20 obese rats and 10 normal rats using Western blot analysis.</p><p><b>RESULTS</b>The relative expression level of GIRK4 protein in the kidney tissues of obese rat (1.75±0.42) was significantly lower than that in normal rats (3.37±0.68, P<0.05).</p><p><b>CONCLUSION</b>GIRK4 has a low protein expression in the kidney tissues of obese rat.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Expression des gènes
/
Canaux potassiques rectifiants entrants
/
Génétique
/
Rein
/
Métabolisme
/
Obésité
Limites du sujet:
Animals
langue:
Zh
Texte intégral:
Acta Academiae Medicinae Sinicae
Année:
2013
Type:
Article