Changes of plasma fibrinogen level among acute ischemic stroke subtypes according to TOAST criteria and effects of Songling Xuemaikang / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1339-1341, 2010.
Article
Dans Chinois
| WPRIM
| ID: wpr-285345
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the changes of plasma fibrinogen level among acute ischemic stroke (ACI) subtypes according to Trial of Org10172 in Acute Stroke Treatment (TOAST) criteria and effects of Songling Xuemaikang.</p><p><b>METHOD</b>The 160 patients with acute ischemic stroke were divided into two groups randomly treatment group 85 cases (Songling Xuemaikang + Shuxuetong + Aspirin enterie coated tablets), control group 75 cases (Shuxuetong + Aspirin enterie ccoated tablets). The plasma fibrinogen was detected before and after treatment.</p><p><b>RESULT</b>Compared with OC subtype, Fbg was higher in LAA, CE and SAO subtypes (P < 0.05). Compared with UE subtype, Fbg was higher in LAA, CE and SAO subtypes (P < 0.05). There was a significantly difference between LAA and SAO (P < 0.05). In LAA, SAO, CE of treatment group,the Fbg level were lowered significantly at the 15th day compared with pretherapy (P < 0.05). There was a significantly difference of Fbg between treatment group and control group In LAA, SAO and CE subtypes at the 15th day (P < 0.05).</p><p><b>CONCLUSION</b>Fbg produces a marked effect at the pathomechanism of LAA, SAO and CE subtypes. Songling Xuemaikang can depress the plasma fibrinogen level of ACI, and be an effective adjunctive therapy on ACI.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Fibrinogène
/
Médicaments issus de plantes chinoises
/
Encéphalopathie ischémique
/
Acide acétylsalicylique
/
Résultat thérapeutique
/
Accident vasculaire cérébral
/
Utilisations thérapeutiques
/
Traitement médicamenteux
/
Métabolisme
Limites du sujet:
Adulte très âgé
/
Aged80
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2010
Type:
Article
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