Your browser doesn't support javascript.
loading
Role of arsenolite on 8-isoprostane of asthmatic mice plasm / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 1758-1760, 2005.
Article Dans Chinois | WPRIM | ID: wpr-287306
ABSTRACT
<p><b>OBJECTIVE</b>Through the establishment of mouse' ovalbumin- sensitized asthmatic model and the observation of the 8-Isoprostane of plasm, to evaluate the therapeutic effects of arsenolite on asthmatic mice.</p><p><b>METHOD</b>Forty-two healthy Kunming male mice were randomly divided into control group and experience groups, the latter were treated with dexamethasone, arsenolite. Lung function were tested, 8-isoprostane of plasm and WBC of BALF were measured.</p><p><b>RESULT</b>Lung function improved after treating with dexamethasone or arsenolite. The WBC of asthmatic mice were significantly higher than those in control group, and decreased after treating with dexamethasone or arsenolite; 8-Isoprostane of plasm in asthmatic mice was higher than that of control group, and decreased after treating with dexamethasone or arsenolite.</p><p><b>CONCLUSION</b>There is oxidant stress status in asthmatic mice. Arsenolite could lighten airway obstruction, reduce airway high response and redress oxidant stress status in asthmatic mice.</p>
Sujets)
Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Oxydes / Pharmacologie / Composés de l&apos;arsenic / Tests de la fonction respiratoire / Asthme / Sang / Liquide de lavage bronchoalvéolaire / Matière médicale / Dinoprost / Répartition aléatoire Limites du sujet: Animaux langue: Chinois Texte intégral: China Journal of Chinese Materia Medica Année: 2005 Type: Article

Documents relatifs à ce sujet

MEDLINE

...
LILACS

LIS

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Oxydes / Pharmacologie / Composés de l&apos;arsenic / Tests de la fonction respiratoire / Asthme / Sang / Liquide de lavage bronchoalvéolaire / Matière médicale / Dinoprost / Répartition aléatoire Limites du sujet: Animaux langue: Chinois Texte intégral: China Journal of Chinese Materia Medica Année: 2005 Type: Article