Advances in the studies of the dysbindin gene in schizophrenia / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 175-178, 2009.
Article
Dans Chinois
| WPRIM
| ID: wpr-287430
ABSTRACT
Recent reports indicate that the dysbindin gene located on chromosome 6p22.3 is a major susceptibility gene for schizophrenia. In the brain, the dysbindin gene may influence glutamatergic neurotransmission by multiple post- and pr- synaptic mechanisms. This paper reviews the research progress on the dysbindin gene in schizophrenia, including the dysbindin gene and its product, the possible pathogenic mechanisms, the association study of the dysbindin gene with schizophrenia, and the cognitive decline caused by the dysbind in variations.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Physiologie
/
Schizophrénie
/
Encéphale
/
Protéines de transport
/
Troubles de la cognition
/
Prédisposition génétique à une maladie
/
Polymorphisme de nucléotide simple
/
Protéines associées à la dystrophine
/
Dysbindine
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Chinese Journal of Medical Genetics
Année:
2009
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS