Coumarins from Skimmia arborescens and its anti-inflammatory effect / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 811-813, 2012.
Article
Dans Chinois
| WPRIM
| ID: wpr-288700
ABSTRACT
To investigate chemical constituents contained in Skimmia arborescens. The chemical constituents were separated by silica gel column chromatography, pharmadex LH-20, RP-C18, and 1H, 13C-NMR spectroscopic analysis were employed for the structural elucidation. Six coumarin compounds were separated from S. arborescens. Their structures were elucidated as umbelliferone (1), scopoletin (2), scopolin (3), nodakenetin (4), skimmin (5), 6, 7-dimethoxycoumarin (6), and all compounds were separated from the plant for the first time. Using the model of ear swelling caused by xylol of mice, the anti-inflammatory effect of its total extract was evaluated. The result indicated that middle and high dose groups of its total extract could obviously inhibit the ear swelling caused by xylol of mice.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Pharmacologie
/
Plantes médicinales
/
Chimie
/
Chromatographie en phase liquide à haute performance
/
Organismes exempts d'organismes pathogènes spécifiques
/
Coumarines
/
Rutaceae
/
Oreille
/
Gel de silice
Type d'étude:
Etude diagnostique
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
China Journal of Chinese Materia Medica
Année:
2012
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS