Detection of anti-Sp17 antibodies in infertile patients' serum and its clinical significance / 中华男科学杂志
National Journal of Andrology
;
(12): 27-29, 2007.
Article
Dans Chinois
| WPRIM
| ID: wpr-289053
ABSTRACT
<p><b>OBJECTIVE</b>To test anti-Sp17 antibodies in the serum of AsAb positive infertile patients, to investigate the proportion of anti-Spl7 antibodies in AsAb and their potential application to the serologic diagnosis of immune infertility and immunocontraception.</p><p><b>METHODS</b>With human recombinant Sp17 as the antigen, the ELISA method was used to detect the positive rate, antibody titre and content of anti-Sp17 antibodies in the AsAb positive serum.</p><p><b>RESULTS</b>The positive rate of anti-Sp17 antibodies in the AsAb positive serum was 56.5%, with no significant difference in the gender aspect. The percentage of anti-Sp17 antibodies in AsAb was (10.09 +/-7.45) %, with statistical significance (P <0.05).</p><p><b>CONCLUSION</b>Sp17 is an important sperm antigen. Anti-Sp17 antibodies in the serum can be taken as auxiliary diagnostic index of infertility, and Sp17 is shown to be a potential candidate immunocontraception vaccine.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Autoanticorps
/
Spermatozoïdes
/
Sang
/
Protéines de transport
/
Immunocontraception
/
Allergie et immunologie
/
Infertilité masculine
/
Antigènes de surface
Type d'étude:
Etude diagnostique
Limites du sujet:
Adulte
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
National Journal of Andrology
Année:
2007
Type:
Article
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