Clinical and laboratory investigation of four acute myeloid leukemia patients with t(3;3) translocation / 中华血液学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the clinical and laboratory characteristics of four acute myeloid leukemia with t(3;3) translocation.</p><p><b>METHODS</b>Bone marrow cell chromosome karyotype analysis were carried out with direct method and short-term culture and R-banding technique.</p><p><b>RESULTS</b>Four AML patients with t(3;3) translocation were identified. They did not obtain complete remission after chemotherapy and the median survival time was 4.5 months.</p><p><b>CONCLUSIONS</b>t(3;3) translocation is a rare chromosome abnormality, which has mostly been found in myeloid leukemia and the prognosis of these patients is poor.</p>