Influence of assisted reproduction technologies on genomic imprinting of embryos and offspring / 中华医学遗传学杂志
Chinese Journal of Medical Genetics
;
(6): 462-465, 2014.
Article
Dans Chinois
| WPRIM
| ID: wpr-291753
ABSTRACT
Assisted reproduction technologies (ART) include controlled ovarian hyperstimulation, in vitro fertilization-embryo transfer, intracytoplasmic sperm injection, in vitro maturation of oocytes, pre-implantation genetic diagnosis, etc. They have been used for the treatment of impaired fertility but may damage the health of offspring. The ART procedures may alter the epigenetic status of these offspring and DNA methylation may be a crucial mechanism. This paper summarizes epigenetic alterations in ART embryos and offspring, and discusses the risks.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Fécondation in vitro
/
Empreinte génomique
/
Méthylation de l'ADN
/
Diagnostic préimplantatoire
/
Embryon de mammifère
/
Métabolisme
Type d'étude:
Etude diagnostique
Limites du sujet:
Animaux
/
Femelle
/
Humains
/
Grossesse
langue:
Chinois
Texte intégral:
Chinese Journal of Medical Genetics
Année:
2014
Type:
Article
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