Detection of differentially expressed genes in hepatocellularcarcinoma cells SMMC-7721 treated with Typhonium giganteum extract by mRNA differential display / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To screen and identify the differentially expressed genes in hepatocellular carcinoma cells SMMC-7721 responsing to the aqueous extract from dried powdered rhizomes of Typhonium giganteum (AEoTGE).</p><p><b>METHOD</b>The response of hepatocellular carcinoma cells SMMC-7721 to AEoTGE was explored with the technique of mRNA differential display.</p><p><b>RESULT</b>After hepatocarcinoma cells SMMC-7721 were treated by AEoTGE for 36 hours, 1 gene expression was upgrade and 1 gene expression was downgrade induced by AEoTGE.</p><p><b>CONCLUSION</b>The research has provided important clues for the molecular mechanism of how hepatocarcinoma cells responseing to T. giganteum.</p>