The relationship between high sensitivity C-reactive protein level at admission and myocardial perfusion after primary percutaneous intervention in patients with acute myocardial infarction / 中华心血管病杂志

ABSTRACT

<p><b>OBJECTIVE</b>This study was designed to investigate the relationship between high sensitivity C-reactive protein (hs-CRP) level at admission and myocardial perfusion after percutaneous coronary intervention (PCI) in patients with acute myocardial infarction.</p><p><b>METHODS</b>The study population consisted of 197 patients (154 men, mean age 60.94 +/- 11.62 years) who were admitted to our hospital with first acute myocardial infarction and underwent primary PCI in the infarct-related artery. Myocardial perfusion was evaluated by Thrombolysis In Myocardial Infarction (TIMI) myocardial perfusion grade (TMPG). Patients were divided into two groups according to TMPG after PCI. Group 1 consisted of 39 patients with TMPG 0 - 1 and group 2 consisted of 158 patients with TMPG 2 - 3. Serum hs-CRP levels at admission were measured.</p><p><b>RESULTS</b>hs-CRP level at admission was significantly higher in group 1 than that in group 2 (P = 0.026).</p><p><b>CONCLUSIONS</b>Higher hs-CRP level at admission in patients with acute myocardial infarction is related to poorer myocardial perfusion post primary PCI.</p>