A study on the relationship between genetic and environmental factors of type 2 diabetes mellitus in humans / 中华预防医学杂志
Chinese Journal of Preventive Medicine
; (12): 191-194, 2002.
Article
de En
| WPRIM
| ID: wpr-295773
Bibliothèque responsable:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the relationship between the inheritable factor and environmental factors of type 2 diabetes mellitus in humans.</p><p><b>METHODS</b>A case-control study based on 154 type 2 diabetes mellitus and 130 healthy controls was carried out in Jiangsu Province in 1997.</p><p><b>RESULTS</b>The age, family history of diabetes mellitus, hypertension history, high waist/hip ratio (WHR), high systolic blood pressure, huge fetus history, and the genotype of beta(3)-adrenergic receptor (beta(3)-AR) were the risk factors of type 2 diabetes mellitus; while occupational physical activity was protective factor of type 2 diabetes mellitus. The risk for diabetes mellitus distinctly increased while genetic factor and obesity, beta(3)-AR mutation were coexisting.</p><p><b>CONCLUSION</b>Type 2 diabetes mellitus is caused by the effect of both genetic and environmental factors.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Études cas-témoins
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Modèles logistiques
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Chine
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Épidémiologie
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Analyse multifactorielle
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Facteurs de risque
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Diabète de type 2
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Environnement
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Génétique
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Obésité
Type d'étude:
Etiology_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limites du sujet:
Aged
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Female
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Humans
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Male
Pays comme sujet:
Asia
langue:
En
Texte intégral:
Chinese Journal of Preventive Medicine
Année:
2002
Type:
Article