Central Diabetes Insipidus Linked to Rathke's Cleft Cyst, Polyuria in a 17-year-old Girl
Electrolytes & Blood Pressure
;
: 23-25, 2017.
Article
Dans Anglais
| WPRIM
| ID: wpr-29647
ABSTRACT
A 17-year-old girl presented with polyuria (7 L/day) and polydipsia for one year. Initial urine osmolality was 113mOsm/kg H₂O. Following 6 h of fluid restriction, serum plasma osmolality reached 300mOsm/kg H₂O, whereas urine osmolality was 108mOsm/kg H₂O. Urine osmolality was increased by 427% from 108 to 557mOsm/kg after vasopressin challenge. The patient was diagnosed with central diabetes insipidus, possibly derived from the atypical occupation of a Rathke's cleft cyst at the pituitary stalk following magnetic resonance imaging with enhancement. She was discharged with desmopressin nasal spray (10 µg); urine output was maintained at 2-3 L/day, and urine osmolality was >300 mOsm/kg. Additional pituitary image studies and evaluation of hypopituitarism should be included in the differential diagnosis of patients with central diabetes insipidus.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Concentration osmolaire
/
Hypophyse
/
Plasma sanguin
/
Polyurie
/
Vasopressines
/
Imagerie par résonance magnétique
/
Diabète insipide central
/
Desmopressine
/
Diagnostic différentiel
/
Polydipsie
Type d'étude:
Etude diagnostique
Limites du sujet:
Adolescent
/
Femelle
/
Humains
langue:
Anglais
Texte intégral:
Electrolytes & Blood Pressure
Année:
2017
Type:
Article
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