BMI and BMI Changes to All-cause Mortality among the Elderly in Beijing: a 20-year Cohort Study / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
;
(12): 79-87, 2017.
Article
Dans Anglais
| WPRIM
| ID: wpr-296512
ABSTRACT
<p><b>OBJECTIVE</b>To explore the association between body mass index (BMI) and all-cause mortality among the elderly in Beijing.</p><p><b>METHODS</b>This analysis was based on the Beijing multidimensional longitudinal study of aging (BLSA), which included 2,090 subjects over 55 years old and was followed-up from 1992 to 2012. BMI-mortality curves were drawn to find the optimal BMI range with the lowest mortality. Cox proportional hazard models were used to obtain the hazard ratios (HRs) for BMI and BMI changes in the overall population and in specific stratified populations.</p><p><b>RESULTS</b>During follow-up, 1,164 deaths were recorded; BMI-mortality curve was U-shaped, with the lowest mortality at a BMI of approximately 25 kg/m2. After adjusting for gender, age, smoking, drinking and some pre-existing diseases, HRs for underweight, overweight and obesity compared with normal weight were 1.372 (95% CI 1.154-1.631), 0.767 (95% CI 0.666-0.884) and 0.871 (95% CI 0.830-1.246), respectively. HR for BMI drop was 3.245 (95% CI 0.824-12.772) in the underweight group and 1.892 (95% CI 0.830-1.246) in the normal weight group, HR for BMI rise was 1.795 (95% CI 1.243-2.591) in normal weight group and 1.962 (95% CI 1.202-3.203) in the overweight group.</p><p><b>CONCLUSION</b>Keeping BMI in an overweight status and stable is related to a reduced mortality.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Indice de masse corporelle
/
Modèles des risques proportionnels
/
Maladie chronique
/
Facteurs de risque
/
Études de cohortes
/
Mortalité
/
Pékin
Type d'étude:
Etude d'étiologie
/
Etude d'incidence
/
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte très âgé
/
Aged80
/
Femelle
/
Humains
/
Mâle
Pays comme sujet:
Asie
langue:
Anglais
Texte intégral:
Biomedical and Environmental Sciences
Année:
2017
Type:
Article
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