Cellular compatibility of type collagen I scaffold and human adipose-derived stem cells / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To study the cellular compatibility of type I collagen scaffold and human adipose-derived stem cells (ADSC(S)) in order to explore appropriate scaffold materials for adipose tissue engineering.</p><p><b>METHODS</b>The morphology and function of the ADSC(S) were observed by inverted phase contrast microscope, scanning electron microscope and XTT assay when cocultured type I collagen scaffold with ADSC(S) in vitro. Cells adhesive rates were also calculated.</p><p><b>RESULT</b>ADSC(S) were able to attach, grow and proliferate well on the scaffolds.</p><p><b>CONCLUSION</b>collagen I scaffold exhibits excellent cellular compatibility and can be used as a vehicle for adipose tissue engineering.</p>