Combined scores of 64 multi-slice CT perfusion characteristics for evaluating solitary pulmonary nodules / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 750-754, 2007.
Article
Dans Chinois
| WPRIM
| ID: wpr-298695
ABSTRACT
<p><b>OBJECTIVE</b>To study the bloody flow mode and the perfusion feature of solitary pulmonary nodules (SPN) on 64 multi-slice CT, and to evaluate the diagnostic value of combined scores in SPN.</p><p><b>METHODS</b>Fifty-two patients with SPN proved by pathology or follow-up underwent dynamic enhancement CT. Perfusion characteristics, including permeability (P), blood flow, blood volume, patlak blood volume, patlak R square (PRS), patlak residual, peak enhancement, perfusion curve, and false color image were analyzed by the body perfusion software. Perfusion characteristics were compared between benign and malignant nodules. Combined scores composed of significant difference observed parameters were used to differentiate benign or malignant SPN.</p><p><b>RESULTS</b>There were significant differences in the enhancement values at 20, 22, 24, 25, 26, 28, 30, and 34s, PRS, I or II type perfusion curve, and marginal uncomplete enhancement or patchy complete enhancement at 34s between benign and malignant SPN. With the multi-variant combined score > 0.5 as the threshold value to differentiate benign and malignant SPN, its sensitivity and specificity was 94.3% and 41.2%, respectively.</p><p><b>CONCLUSION</b>The combined scores of 64 multi-slice CT can help differentiate the benign or malignant SPN.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Perméabilité
/
Volume sanguin
/
Mesure du volume sanguin
/
Imagerie diagnostique
/
Tomodensitométrie
/
Nodule pulmonaire solitaire
/
Hémodynamique
/
Tumeurs du poumon
Type d'étude:
Etude diagnostique
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Acta Academiae Medicinae Sinicae
Année:
2007
Type:
Article
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