Identification and expression of non-coding RNAs NC28 and NC119 in human tumors / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 618-621, 2007.
Article
Dans Zh
| WPRIM
| ID: wpr-298771
Responsable en Bibliothèque :
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore and identify the non-coding RNAs related to tumors.</p><p><b>METHODS</b>We used RT-PCR and Northern blot to analyze non-coding RNAs in tumor tissues and cell lines.</p><p><b>RESULTS</b>Two predicted non-coding RNAs were confirmed to be expressed in cancer tissues and cell lines by RT-PCR and DNA sequencing. We detected the expression of two non-coding RNA transcripts by Northern blot. The length of NC28 was about 1800 nt, and that of NC119 was about 1200nt.</p><p><b>CONCLUSIONS</b>NC28 and NC119 have a tumor-associated expression pattern. The non-coding RNAs may play a role in the development of tumors.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
ARN non traduit
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Lignée cellulaire tumorale
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Métabolisme
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Tumeurs
Limites du sujet:
Humans
langue:
Zh
Texte intégral:
Acta Academiae Medicinae Sinicae
Année:
2007
Type:
Article