Intervention of antioxidant system function of aged rats by giving fruit juices with different antioxidant capacities / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 80-83, 2005.
Article
Dans Chinois
| WPRIM
| ID: wpr-299195
ABSTRACT
<p><b>OBJECTIVE</b>To observe the effects of fruit juices with different antioxidant capacity on antioxidant system function of aged rats.</p><p><b>METHODS</b>Thirty Wistar rats were randomly divided into three groups pomegranate juice and apple juice as two experimental groups, while distilled water as normal control group. They were administrated fruit juices or distilled water respectively by gavage daily for 4 weeks. At the end of experiment, the antioxidant system function was assessed.</p><p><b>RESULTS</b>The aged rats in pomegranate juice group showed significantly higher serum antioxidant capacity (0.90 +/- 0.13) mmol/L than that in control group (0.79 +/- 0.10) mmol/L (P < 0.05). The concentrations of serum carbonyl and oxLDL were decreased significantly in pomegranate juice group as compared to the control group (P < 0.05). The percentage of injured blood lymphocyte DNA and the ratio of tail length/total length were declined significantly in pomegranate juice group (P < 0.05 and P < 0.01 respectively). The apple juice showed no effects except decreased ratio of tail length/total length of injured lymphocyte DNA. There were no changes in concentrations of serum vitamin C, vitamin E, urinary 8-OH-dG excretion and the activities of serum SOD, GSH-Px, CAT among three groups.</p><p><b>CONCLUSIONS</b>The pomegranate juice should possess higher antioxidant capacity and might improve the antioxidant system function of aged rats, while the apple juice is relatively lower in antioxidant capacity and not very effective. The polyphenols in pomegranate juice might be the important functional components.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Acide ascorbique
/
Superoxide dismutase
/
Urine
/
Vitamine E
/
Boissons
/
Sang
/
Vieillissement
/
Lymphocytes
/
Catalase
/
Répartition aléatoire
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
Chinese Journal of Preventive Medicine
Année:
2005
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS