Clinical significance of regional lymphadenectomy in radical resection of ductal adenocarcinoma in the pancreatic head / 中华外科杂志
Chinese Journal of Surgery
;
(12): 324-327, 2003.
Article
Dans Chinois
| WPRIM
| ID: wpr-300040
ABSTRACT
<p><b>OBJECTIVE</b>To prospectively evaluate the long-term effect of pancreaticoduodenectomy with regional lymphadenectomy.</p><p><b>METHODS</b>One hundred and twenty-one patients with ductal adenocarcinoma in the pancreatic head treated from 1996 to 2001 were studied prospectively. The enrollment of the patients was dependent on 7 criteria. The patients were divided into two groups regional lymphadenectomy (group A, n = 50) and routine Whipple procedure (group B, n = 71). Their pre- and postoperative conditions, clinicopathological data, survival rates were studied.</p><p><b>RESULTS</b>It was comparable between the 2 groups in age, sex, preoperative risk factors, operative management, and postoperative complication. Clinicopathological results showed no difference in tumor size and plexus invasion; but the frequency of lymph node involvement and the amount of resected lymph node in group A were significantly higher than those in group B. The rate of local recurrence was significantly higher in group A than in group B. The survival rates of 1-, 3-, 5-year in group A were 70.8%, 31.4%, 20.9%, respectively, which were higher than those in group B. No direct relations were observed between nodal involvement and survival rate.</p><p><b>CONCLUSION</b>Lymphadenectomy in radical pancreaticoduodenectomy could remove lymph nodes effectively and sufficiently, and reduce the rate of local recurrence so as to improve the long-term survival rate.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Tumeurs du pancréas
/
Anatomopathologie
/
Chirurgie générale
/
Études prospectives
/
Études de suivi
/
Résultat thérapeutique
/
Duodénopancréatectomie
/
Estimation de Kaplan-Meier
/
Lymphadénectomie
/
Récidive tumorale locale
Type d'étude:
Étude observationnelle
/
Étude pronostique
/
Facteurs de risque
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Chinese Journal of Surgery
Année:
2003
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS