Research progresses in the pathogenesis, diagnosis and treatment of infantile hemangioma with PHACE syndrome / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 1291-1296, 2017.
Article
Dans Chinois
| WPRIM
| ID: wpr-300405
ABSTRACT
Infant hemangioma, the most common benign tumor in children, is characterized by rapid proliferation, followed by slower spontaneous involution. However, some patients with facial segmental hemangioma are associated with PHACE syndrome. PHACE syndrome is characterized by vascular nerve and vascular cutaneous lesions of multiple systemic systems, often resulting in structural and functional impairments. Recent studies have demonstrated that the possible pathogeneses of PHACE syndrome mainly include hypoxia, abnormality of mesodermal vascular endothelial cells, genetic abnormality, and abnormality of interstitial mesenchymal stem cells. The current medications for hemangioma with PHACE syndrome include beta blockers, glucocorticoids, and mTOR inhibitors. This review article mainly describes the pathogenesis, diagnoses and treatments of PHACE syndrome, in order to provide directions for diagnosis and treatment of this disorder.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Thérapeutique
/
Malformations multiples
/
Malformations oculaires
/
Diagnostic
/
Cardiopathies congénitales
/
Hémangiome
Type d'étude:
Etude diagnostique
/
Etude d'étiologie
Limites du sujet:
Humains
/
Bébé
langue:
Chinois
Texte intégral:
Chinese Journal of Contemporary Pediatrics
Année:
2017
Type:
Article
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