Human protamines and the developing spermatid: their structure, function, expression and relationship with male infertility / 亚洲男科学杂志(英文版)
Asian Journal of Andrology
;
(6): 315-324, 2003.
Article
Dans Anglais
| WPRIM
| ID: wpr-300879
ABSTRACT
During spermiogenesis, the protamine proteins play an integral role in spermatid chromatin compaction. Recent research has focused on many facets of protamine biology, including protamine gene and protein structure/function relationships, mechanisms of protamine expression regulation and involvement of the protamines in male fertility. In this paper, we review our current understanding of the structure and function of the protamine-1 (P1) and protamine-2 (P2) proteins and genes, the expression and regulation of these genes and the relationship between the protamines and male fertility. In addition, we offer a brief outlook on future investigation into protamine proteins.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Physiologie
/
Spermatides
/
Données de séquences moléculaires
/
Protamine
/
Chimie
/
Régulation de l'expression des gènes
/
Séquence d'acides aminés
/
Génétique
/
Infertilité masculine
/
Métabolisme
Limites du sujet:
Humains
/
Mâle
langue:
Anglais
Texte intégral:
Asian Journal of Andrology
Année:
2003
Type:
Article
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