Pleiotropic effects of herbs characterized with blood-activating and stasis-resolving functions on angiogenesis / 中国结合医学杂志
Chinese journal of integrative medicine
; (12): 795-800, 2016.
Article
Dans En
| WPRIM
| ID: wpr-301065
Responsable en Bibliothèque :
WPRO
ABSTRACT
Accumulative evidences have underpinned the nature candidates from Chinese medicine (CM), particularly CM served as blood activating and stasis resolving (BASR, Huoxue Huayu in Chinese) by targeting tumor-associated angiogenesis. However, recent experiment research on the therapeutic angiogenesis by BASR-CM attracts wide attention and discussion. This opinion review focused on the underlying link between two indications and anticipated that (1) BASR-CM might emphasize on a balanced multi-cytokines network interaction; (2) BASR-CM might address on the nature of diseases prior to differently affecting physiological and pathological angiogenesis; (3) BASR-CM might mainly act on perivascular cells, either promotes arteriogenesis by increasing arteriogenic factors in ischemic diseases, or simultaneously keep a quiescent vasculature to impede angiogenesis in tumor context.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Sang
/
Médicaments issus de plantes chinoises
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Chimie
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Inhibiteurs de l'angiogenèse
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Utilisations thérapeutiques
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Traitement médicamenteux
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Modèles biologiques
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Néovascularisation pathologique
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Antinéoplasiques
Type d'étude:
Prognostic_studies
Limites du sujet:
Animals
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Humans
langue:
En
Texte intégral:
Chinese journal of integrative medicine
Année:
2016
Type:
Article