Is Chinese herbal medicine effective for elderly isolated systolic hypertension? A systematic review and meta-analysis / 中国结合医学杂志
Chinese journal of integrative medicine
;
(12): 298-305, 2017.
Article
Dans Anglais
| WPRIM
| ID: wpr-301078
ABSTRACT
<p><b>OBJECTIVE</b>To study the efficacy of Chinese medicine (CM) on isolated systolic hypertension.</p><p><b>METHODS</b>Seven electronic databases were searched for randomized controlled trials (RCTs) published until August 2015. Subgroup analyses and meta-analysis were performed to assess the efficacy and safety of the included studies.</p><p><b>RESULTS</b>A total of 24 studies, including 2,096 patients (1,058 patients in the intervention group and 1,038 in the control group), were evaluated in the final analysis. Compared with a conventional therapy used alone, CM as additional intervention was more effective on systolic blood pressure [mean difference (MD)=-0.66, 95% confidence interval (CI)=(-0.97,-0.36), P<0.00001] and significantly diminished the pulse pressure [MD=-7.49, CI=(-12.69,-2.29), P<0.00001]. However it showed no additional benefit on diastolic blood pressure [MD=1.16, CI=(0.02, 2.29), P=0.87]. Adverse events were not explicitly reported in most RCTs.</p><p><b>CONCLUSIONS</b>CM might be a promising approach for the elderly with isolated systolic hypertension, while the evidence for CM employed alone was insufficient. Considering the inherent limitations of the included studies, larger high-quality RCTs with extensive follow-up should be performed to validate our findings in the future.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pouls
/
Systole
/
Pression sanguine
/
Médicaments issus de plantes chinoises
/
Essais cliniques comme sujet
/
Résultat thérapeutique
/
Biais de publication
/
Utilisations thérapeutiques
/
Traitement médicamenteux
/
Hypertension artérielle
Type d'étude:
Essai clinique contrôlé
/
Revues systématiques évaluées
Limites du sujet:
Adulte très âgé
/
Humains
langue:
Anglais
Texte intégral:
Chinese journal of integrative medicine
Année:
2017
Type:
Article
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