Chemical constituents of Ligularia dictyoneura / 药学学报

ABSTRACT

<p><b>AIM</b>To study the chemical constituents of Ligularia dictyoneura.</p><p><b>METHODS</b>Various chromatographic techniques were used to separate and purify the compounds. Their spectral data (MS, IR, NMR) were measured for structure elucidation.</p><p><b>RESULTS</b>Four sesquiterpenes were isolated from Ligularia dictyoneura and their structures were identified as ligudicin A (1), ligudicin C (2), ligudicin D (3) and isopetasin (4).</p><p><b>CONCLUSION</b>Compound 1 is a new compound, compound 2 is a new natural product, and compounds 3 and 4 are obtained from Ligularia dictyoneura for the first time.</p>