Research Advances in the Epigenetics of Diffuse Large B-Cell Lymphoma-Review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1232-1236, 2017.
Article
Dans Chinois
| WPRIM
| ID: wpr-301746
ABSTRACT
The pathogenesis of diffuse large B-cell lymphoma(DLBCL) has not been fully elucidated, but people realized that the occurrence of DLBCL is caused by the mutual change of genetics and epigenetics with the rapid development of modern biological technology. Epigenetics is to explore the expression changes of genes and proteins without the changes of gene sequences, and this change is reversible and can be inherited. In this review, the latest advances of epigenetic changes in DNA methylation, microRNA regulation, and histone modification for DLBCL are summarized, so as to provide a new strategy to study the early diagnosis, treatment and prognosis of DLBCL.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Étude de dépistage
langue:
Chinois
Texte intégral:
Journal of Experimental Hematology
Année:
2017
Type:
Article
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