Expression of vascular cell adhesion molecule-1 in patients with multiple myeloma and its significance / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 382-384, 2009.
Article
Dans Chinois
| WPRIM
| ID: wpr-302128
ABSTRACT
In order to investigate the expression of vascular cell adhesion molecule-1 (VCAM-1) in patients with multiple myeloma and its significance, the expression of VCAM-1 in 23 patients were detected by reverse transcription-PCR (RT-PCR) and then compared with that in normal control. The results showed that the expression of VCAM-1 in patients with newly diagnosed and relapsed/refractory multiple myeloma was much higher than that in normal control and in patients reached plateau stage (p < 0.05). There was no statistically significant difference between newly diagnosed and relapsed/refractory patients (p > 0.05). It is concluded that the expression of VCAM-1 in patients with multiple myeloma is abnormal, which may be an important factor for the pathogenesis of multiple myeloma.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Études cas-témoins
/
Molécule-1 d'adhérence des cellules vasculaires
/
RT-PCR
/
Métabolisme
/
Myélome multiple
/
Stadification tumorale
Type d'étude:
Étude observationnelle
Limites du sujet:
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Journal of Experimental Hematology
Année:
2009
Type:
Article
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