New insight into DNA methylation in CML and its effect on clinical outcome--review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1482-1486, 2008.
Article
Dans Chinois
| WPRIM
| ID: wpr-302211
ABSTRACT
All kinds of tumors have their specific DNA methylation patterns. The study of DNA methylation changes in chronic myelogenous leukemia includes (1) the hypomethylation of carcinogenic gene, (2) the hypermethylation of tumor-suppressing gene, and (3) the hypermethylation of fusion gene. In this paper, DNA methylation change in chronic myeloid leukemia (CML) and its role in clinical stages and evaluation of prognosis were reviewed so as to illuminate the relationship between DNA methylation and CML.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Pronostic
/
Leucémie myéloïde chronique BCR-ABL positive
/
Méthylation de l'ADN
/
Diagnostic
/
Génétique
Type d'étude:
Etude diagnostique
/
Étude pronostique
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Experimental Hematology
Année:
2008
Type:
Article
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