Congenital Aniridia: Long-term Clinical Course, Visual Outcome, and Prognostic Factors
Korean Journal of Ophthalmology
;
: 479-485, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-30314
ABSTRACT
PURPOSE:
To describe the clinical course of congenital aniridia and to evaluate prognostic factors for visual outcome after long-term follow-up.METHODS:
The medical records of 120 eyes from 60 patients with congenital aniridia were retrospectively reviewed. The prevalence and clinical course of ophthalmic characteristics, systemic disease, refractive errors, and visual acuity were assessed. Prognostic factors for final visual outcomes were analyzed.RESULTS:
Aniridic keratopathy developed in 82 (69%) of 119 eyes. Macular hypoplasia was observed in 70 eyes of 35 patients (91%). Cataract was observed in 63 of 120 eyes (53%). Nystagmus was present in 41 patients (68% of 60 patients) at the initial visit but decreased in five patients (8% of 60 patients). Ocular hypertension was detected in 19 eyes (20% of 93 eyes), six (32% of 19 eyes) of which developed secondarily after cataract surgery. The mean changes in spherical equivalent and astigmatism during the follow-up period were -1.10 and 1.53 diopter, respectively. The mean final visual acuity was 1.028 logarithm of minimal angle of resolution. Nystagmus and ocular hypertension were identified as prognostic factors for poor visual outcome.CONCLUSIONS:
Identification of nystagmus and ocular hypertension was important to predict final visual outcome. Based on the high rate of secondary ocular hypertension after cataract surgery, careful management is needed.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pronostic
/
Rétine
/
Cataracte
/
Acuité visuelle
/
Aniridie
/
Malformations oculaires
/
Nystagmus pathologique
/
Hypertension oculaire
/
Études rétrospectives
/
Études de suivi
Type d'étude:
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Adolescent
/
Adulte
/
Enfant
/
Enfant d'âge préscolaire
/
Humains
/
Bébé
/
Nouveau-né
langue:
Anglais
Texte intégral:
Korean Journal of Ophthalmology
Année:
2014
Type:
Article
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