Clinical and experimental study on separately decocted and mingly decocted jianweishu granule / 中国中西医结合杂志

ABSTRACT

<p><b>OBJECTIVE</b>To observe the difference in therapeutic effect of Chinese herbal granule decocted separately and mingly.</p><p><b>METHODS</b>One hundred patients of functional dyspepsia of Spleen deficiency and Liver stagnancy type were treated with Jianweishu Granule (JWSG, a self-formulated recipe by the author). Half of the patients received JWSG decocted separately, half of them received that decocted mingly. The therapeutic effects between the two groups were compared. Experimental observation on the effects of differently decocted remedies in rats was also conducted.</p><p><b>RESULTS</b>The therapeutic effects obtained in the two groups were similar, with respective cure rate of 72% and 70% and the total effective rate 96% in both group. There was insignificant difference between the two groups (P > 0.05). Experimental study all showed no difference between the differently decocted remedies in inhibiting gastric acid, pepsin activity, gastric function regulation, small intestine movement improvement and pain alleviation in rats.</p><p><b>CONCLUSION</b>The therapeutic effects of JWSG decocted separately or mingly are the same. This fact provides a scientific basis for clinical use of granule form of single Chinese herbs.</p>