Influence of the number of removed axillary lymph nodes on the prognosis of node-negative primary breast cancer / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 457-460, 2012.
Article
Dans Chinois
| WPRIM
| ID: wpr-307364
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the relationship between the number of removed axillary lymph nodes and prognosis of axillary node-negative breast cancer.</p><p><b>METHODS</b>The clinicopathological data of 655 patients with breast cancer were analyzed retrospectively. The disease-free survival curves were generated according to the number of removed axillary lymph nodes using Kaplan-Meier plots. The correlation between the co-variables and rate of breast cancer-related events was analyzed using Cox model.</p><p><b>RESULTS</b>The overall five year-disease free survival rate of the 655 cases was 94.4%. The rate of patients with lymph node number ≤ 12 was 90.3%, and that of lymph node number > 12 was 96.5%, with a statistically significant difference (P = 0.009). Significantly less breast cancer-related events were observed in patients with lymph node number > 12 (15/426, 3.5%) than that in patients with lymph node number ≤ 12 (22/229, 9.6%) (P = 0.009).</p><p><b>CONCLUSIONS</b>When axillary node dissection is indicated, dissection of lymph nodes >12 leads to much less breast cancer-related events than that in patients with dissected lymph node ≤ 12. The more lymph nodes are dissected, the more accurate prognosis can be estimated.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Aisselle
/
Chirurgie générale
/
Tumeurs du sein
/
Modèles des risques proportionnels
/
Taux de survie
/
Études rétrospectives
/
Études de suivi
/
Carcinome canalaire du sein
/
Carcinome intracanalaire non infiltrant
Type d'étude:
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Adulte
/
Femelle
/
Humains
langue:
Chinois
Texte intégral:
Chinese Journal of Oncology
Année:
2012
Type:
Article
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