Hematological alterations in 10 aplastic anemia patients splenectomized at NIHBT in 1996-1997

ABSTRACT

During two years we carried out the technique of splenectomy for 10 patients with idiopathic aplastic anemia AA. All patients were refractory after 3 courses of immunosuppressive drugs and androgen. Investigation on clinical aspects and hematological parameters after splenectomy, we found that all blood cells counts tend to be increased forward recovery. We are now continuing to further evaluation on hematopoiesis and lymphocytic subsets distribution, in order to select patients group, suitable to this technique.