Progess on research of herpes simplex virus type 1 mutants for cancer therapy / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 1446-1449, 2008.
Article
Dans Chinois
| WPRIM
| ID: wpr-318132
ABSTRACT
For a long time past viruses have been recognized as being tumoricidal. At present, researchers are still pursuing studies and constructing more suitable oncolytic viruses for treating different malignant tumors. Herpes simplex virus type 1 (HSV-1) has been known as the most potential oncolytic virus among all the viruses. In this overview, we summarize the current situation of oncolytic viruses, the biology of HSV-1, its construction and application of its recombinant, and we debate on the feasibility and prospect of HSV-1 mutants labeled with radionuclides for cancer therapy.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Physiologie
/
Radiothérapie
/
Herpèsvirus humain de type 1
/
Virus oncolytiques
/
Thérapie virale de cancers
/
Génétique
/
Méthodes
/
Mutation
/
Tumeurs
Limites du sujet:
Humains
langue:
Chinois
Texte intégral:
Journal of Biomedical Engineering
Année:
2008
Type:
Article
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