Meta-analysis on the relationship of chlamydia pneumonia infection and coronary heart disease / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To determine the relationship of chlamydia pneumonia (CP) infection and coronary heart disease (CHD).</p><p><b>METHODS</b>Studies published before 2004 that had reported on correlations between CHD and CP were collected. Studies were sorted into four sorts according to different testing methods. We determined to use either fixed effect model or random effect model according to the result of heterogeneity test. Meta-analysis was done by RevMan 4.2.</p><p><b>RESULTS</b>Totally 29 studies were included into the review. The odd ratio (OR) to review all literature enzyme-linked immunosorbent assay (ELISA), dot-immunogdd filtration assay (DIGFA), and micro-immunofluorescence (MIF) was 4.00 (3.07, 5.22), 2.86 (1.89, 4.32), 14.89 (1.46, 151.57), and 4.46 (3.15, 6.32).</p><p><b>CONCLUSION</b>CP infection is associated with CHD, CP infection may be one of the risk factors of CHD.</p>