Expression of matrixmetalloproteinase-8 on the bell-stage in human and rat tooth development / 华西口腔医学杂志
West China Journal of Stomatology
; (6): 26-28, 2004.
Article
Dans Zh
| WPRIM
| ID: wpr-319068
Responsable en Bibliothèque :
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the expression of MMP-8 in human and rat tooth development.</p><p><b>METHODS</b>Immunohistochemistry was used to detect the localization of MMP-8 protein while in situ hybridization was used to examine the expression of MMP-8 mRNA.</p><p><b>RESULTS</b>The expression of MMP-8 protein was localized in odontoblast and dentin matrix at the later bell stage in human tooth germ. The dentin was denser close to the pulp cavity. The expression of MMP-8 mRNA was found in very few polarized odontoblast at the early bell stage and all polarized odontoblast at the later bell stage in rat tooth germ.</p><p><b>CONCLUSION</b>The results suggested that MMP-8 involved in dentin matrix rebuilding in the process of dentin formation in human and rat dental development.</p>
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Germe dentaire
/
ARN messager
/
Embryologie
/
Rat Sprague-Dawley
/
Hybridation in situ
/
Matrix metalloproteinase 8
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Dentine
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Embryon de mammifère
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Génétique
/
Animaux nouveau-nés
Limites du sujet:
Animals
langue:
Zh
Texte intégral:
West China Journal of Stomatology
Année:
2004
Type:
Article