Ultrasonography and magnetic resonance imaging for diagnosis of neonatal agenesis of the corpus callosum: a comparative study / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To summarize the ultrasonography features of neonate corpus callosum agenesis for better diagnosis of this condition.</p><p><b>METHODS</b>A total of 8563 neonates were screened by cerebral ultrasound in neonate care unit of our hospital from June 2010 to December 2012, and 37 cases of agenesis of the corpus callosum were identified. The diagnostic accuracy of ultrasonography and magnetic resonance imaging (MRI) for this condition was evaluated.</p><p><b>RESULTS</b>The sensitivity, specificity, and accuracy of ultrasound diagnosis for complete and incomplete absence of neonate corpus callosum were 100% and 90%, 90.9% and 94.1%, 94.6% and 91.9% in the 37 cases, respectively. The Kappa value of ultrasonography and MRI were 0.890 and 0.837, with a consistent rate of 91%.</p><p><b>CONCLUSION</b>Ultrasonography and MRI show a high consistency in the diagnosis of neonatal agenesis of the corpus callosum.</p>