Your browser doesn't support javascript.
loading
Protective effect of epigallocatechin gallate against sperm abnormality in mice / 中华男科学杂志
National Journal of Andrology ; (12): 1068-1072, 2014.
Article Dans Chinois | WPRIM | ID: wpr-319566
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the protective effect of epigallocatechin gallate (EGCG) on mouse sperm in vivo.</p><p><b>METHODS</b>A total of 64 six-week-old male Kuming mice were randomly divided into eight groups of equal number to be treated with normal saline (negative control), Cyclophosphamide (CP) at 30 mg/kg (positive control), and CP followed by EGCG (experimental) at 20, 40, and 80 mg/kg, respectively, given every other day for 10 days. At 4 and 5 weeks after treatment, the bilateral testes of the mice were harvested for examination of sperm abnormality.</p><p><b>RESULTS</b>EGCG did not increase the rate of CP-induced sperm abnormality in the mice, but reduced it instead with the prolonged time of treatment.</p><p><b>CONCLUSION</b>EGCG protects mouse sperm in vivo.</p>
Sujets)
Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Pharmacologie / Spermatozoïdes / Facteurs temps / Répartition aléatoire / Catéchine / Cyclophosphamide / Toxicité / Mutagènes Limites du sujet: Animaux langue: Chinois Texte intégral: National Journal of Andrology Année: 2014 Type: Article

Documents relatifs à ce sujet

MEDLINE

...
LILACS

LIS

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Pharmacologie / Spermatozoïdes / Facteurs temps / Répartition aléatoire / Catéchine / Cyclophosphamide / Toxicité / Mutagènes Limites du sujet: Animaux langue: Chinois Texte intégral: National Journal of Andrology Année: 2014 Type: Article