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TRPP subfamily and kidney diseases / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences ; (6): 650-656, 2010.
Article Dans Chinois | WPRIM | ID: wpr-319843
ABSTRACT
TRPP subfamily is an important member of transient receptor potential family. It has six transmembrane (TM) domains, a large extracellular loop between the first and second TM and 2-4 ankyrin repeats in the N terminal. TRPP subfamily includes TRPP2, TRPP3, TRPP5 etc. There are several differences in their structure, activation mode and function. TRPP subfamily is involved in many physiological mechanisms and its abnormal structure can lead to the formation of polycystic kidney. This subfamily is also closely related to gustation. In this review, we summarize recent research findings of TRPP subfamily and its association with polycystic kidney diseases.
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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Physiologie / Chimie / Canaux cationiques TRPP / Génétique / Polykystoses rénales / Métabolisme Limites du sujet: Humains langue: Chinois Texte intégral: Journal of Zhejiang University. Medical sciences Année: 2010 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Sujet Principal: Physiologie / Chimie / Canaux cationiques TRPP / Génétique / Polykystoses rénales / Métabolisme Limites du sujet: Humains langue: Chinois Texte intégral: Journal of Zhejiang University. Medical sciences Année: 2010 Type: Article