Research advances on associated genes and pathogenesis of hydrocephalus / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 644-649, 2010.
Article
Dans Chinois
| WPRIM
| ID: wpr-319844
ABSTRACT
Hydrocephalus is a common medical condition characterized by abnormalities in the secretion,circulation or resorption of cerebrospinal fluid (CSF), resulting in ventricular dilatation. The pathogenetic mechanism for the hydrocephalus is attributed to the overproduction of CSF by the choroid plexus; the defect in CSF absorption and obstruction of CSF flow in the cerebral ventricles. However, the underlying etiology is poorly understood. With the development of genetic engineering, a growing body of evidence indicates that genetic factors play an essential role in the pathogenesis of hydrocephalus. It is the aim of this review to summarize these findings.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Anatomopathologie
/
Ventricules cérébraux
/
Souris knockout
/
Modèles animaux de maladie humaine
/
Génétique
/
Hydrocéphalie
Type d'étude:
Etude d'étiologie
/
Étude pronostique
Limites du sujet:
Animaux
langue:
Chinois
Texte intégral:
Journal of Zhejiang University. Medical sciences
Année:
2010
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS