Relationship between hepatitis B virus DNA and hepatitis B virus large envelope protein / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 386-389, 2010.
Article
Dans Chinois
| WPRIM
| ID: wpr-319890
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship between HBV DNA and hepatitis B virus large envelope protein (HBV-LP) in patients with chronic hepatitis B.</p><p><b>METHODS</b>Serum HBV DNA was detected by RT-PCR and the HBV-LP was detected by enzyme linked immunosorbent assay in 320 serum samples collected from patients with chronic hepatitis B.</p><p><b>RESULTS</b>There were no significant difference between positive rate of HBV-LP and that of HBV DNA in different HBeAg patterns (P>0.05). Serum HBV-LP levels were closely correlated with HBV DNA copies (r=0.949).</p><p><b>CONCLUSION</b>Serum HBV-LP is a reliable serological marker that can reflect the replication of HBV.</p>
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Physiologie
/
Virologie
/
Réplication virale
/
Sang
/
ADN viral
/
Protéines de l'enveloppe virale
/
Virus de l'hépatite B
/
Hépatite B chronique
Limites du sujet:
Adolescent
/
Adulte
/
Adulte très âgé
/
Femelle
/
Humains
/
Mâle
langue:
Chinois
Texte intégral:
Journal of Zhejiang University. Medical sciences
Année:
2010
Type:
Article
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