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Serogroup and Antimicrobial Resistance of Streptococcus pneumoniae Isolated from Oropharynx in Children Attending Day Care Center
Article de Ko | WPRIM | ID: wpr-32003
Bibliothèque responsable: WPRO
ABSTRACT
PURPOSE: Penicillin- and multidrug-resistant S. pneumoniae poses a serious threat to clinicians because the rate of resistance of S. pneumoniae to penicillin in Korea has surged up to the world's highest level. This study was performed to assess the carriage rate, serogroups and antimicrobial susceptibility of S. pneumoniae isolated from oropharynx in children. METHODS: From March to July 1998, 209 children under 5 years of age were recruited from five day care centers. The carriage rate for pneumococci was obtained. Antimicrobial susceptibilities were determined with the E-test and agar dilution methods. Serogrouping was performed on 48 of the pneumococcal isolates by the Quellung reaction. RESULTS: The carriage rate of S. pneumoniae was 30.1%. Antimicrobial susceptibility profiles were available for 59 of the isolates. Sixty-six percent of isolates were not susceptible to penicillin, and multidrug-resistance was observed in 76.3% of the isolates. A high proportion of the penicillin-resistant strains showed associated resistance to trimethoprim-sulfamethoxazole, tetracycline, erythromycin, and oxacillin. The most prevalent oropharyngeal serogroups were 19, 6, 3, 23, and 29. Resistance of the pneumococcal isolates to penicillin was different according to the serogroups. All of the strains of serogroup 19, 23, and 29 was resistant to penicillin but 87.5% of serogroup 3 strains were susceptible to penicillin. CONCLUSION: The resistance rate of S. pneumoniae isolated from oropharynx in children was very high to penicillin and other antimicrobial agents. For the reduction of the drug-resistant rate of S. pneumoniae, clinicians should be required to be more judicious in their use of antimicrobial agents.
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Mots clés
Texte intégral: 1 Indice: WPRIM Sujet Principal: Partie orale du pharynx / Oxacilline / Pénicillines / Pneumopathie infectieuse / Streptococcus / Streptococcus pneumoniae / Tétracycline / Association triméthoprime-sulfaméthoxazole / Érythromycine / Soins de jour Limites du sujet: Child / Humans Pays comme sujet: Asia langue: Ko Texte intégral: Journal of the Korean Pediatric Society Année: 2002 Type: Article
Texte intégral: 1 Indice: WPRIM Sujet Principal: Partie orale du pharynx / Oxacilline / Pénicillines / Pneumopathie infectieuse / Streptococcus / Streptococcus pneumoniae / Tétracycline / Association triméthoprime-sulfaméthoxazole / Érythromycine / Soins de jour Limites du sujet: Child / Humans Pays comme sujet: Asia langue: Ko Texte intégral: Journal of the Korean Pediatric Society Année: 2002 Type: Article