Cancers of the lung, head and neck on the rise: perspectives on the genotoxicity of air pollution / 癌症
Chinese Journal of Cancer
; (12): 476-480, 2014.
Article
de En
| WPRIM
| ID: wpr-320513
Bibliothèque responsable:
WPRO
ABSTRACT
Outdoor air pollution has been recently classified as a class I human carcinogen by the World Health Organization (WHO). Cumulative evidence from across the globe shows that polluted air is associated with increased risk of lung, head and neck, and nasopharyngeal cancers--all of which affect the upper aerodigestive tract. Importantly, these cancers have been previously linked to smoking. In this article, we review epidemiologic and experimental evidence of the genotoxic and mutagenic effects of air pollution on DNA, purportedly a key mechanism for cancer development. The alarming increase in cancers of the upper aerodigestive tract in Asia suggests a need to focus government efforts and research on reducing air pollution, promoting clean energy, and investigating the carcinogenic effects of air pollution on humans.
Texte intégral:
1
Indice:
WPRIM
Sujet Principal:
Asie
/
Altération de l'ADN
/
Cancérogènes
/
Fumer
/
Tumeurs du rhinopharynx
/
Mutagenèse
/
Pollution de l'air
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Tumeurs de la tête et du cou
/
Tumeurs du poumon
Limites du sujet:
Humans
Pays comme sujet:
Asia
langue:
En
Texte intégral:
Chinese Journal of Cancer
Année:
2014
Type:
Article